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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Ep-CAM / CD326 (Epithelial Marker) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM00993G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Ep-CAM / CD326 (Epithelial Marker) Antibody - With BSA and Azide.
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分子量 |
40-43kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
EGP40/837
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亞型 |
Mouse / IgG1, kappa
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通用名 |
GA733-2, M1S2, M4S1, MIC18, TACSTD1, TRO
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基因ID |
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UniProt ID |
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功能 |
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
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總結(jié) |
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, FC
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圖像 |
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說明書 |
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數(shù)量 |
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