Androgen Receptor (Marker of Androgen Dependence) Antibody - With BSA and Azide

AMM00927G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM00927G		50 ug / ￥3950

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安諾倫（北京）生物科技有限公司

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Androgen Receptor (Marker of Androgen Dependence) Antibody - With BSA and Azide

品牌	Leading Biology	貨號	AMM00927G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Androgen Receptor (Marker of Androgen Dependence) Antibody - With BSA and Azide.
分子量	110kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	AR441
亞型	Mouse / IgG1, kappa
通用名	DHTR, NR3C4
基因ID	367
UniProt ID	P10275
功能	Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
總結(jié)	Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.?This MAb is superb for staining of formalin/paraffin tissues.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC, IF, FC
圖像	Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Androgen Receptor Monoclonal Antibody (AR441).
說明書	Product Datasheet Protocol
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Androgen Receptor (Marker of Androgen Dependence) Antibody - With BSA and Azide