Chromogranin A / CHGA (Neuroendocrine Marker) Antibody - With BSA and Azide

AMM00153G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM00153G		50 ug / ￥3950

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安諾倫（北京）生物科技有限公司

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Chromogranin A / CHGA (Neuroendocrine Marker) Antibody - With BSA and Azide

品牌	Leading Biology	貨號	AMM00153G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Chromogranin A / CHGA (Neuroendocrine Marker) Antibody - With BSA and Azide.
分子量	68-75kDa
細胞定位	Antigen Cellular Localization: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle membrane. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions.
宿主	Mouse
種屬反應(yīng)性	Human, Mouse, Rat
靶點	Human pheochromocytoma (LK2H10 & PHE5) & recombinant human chromogranin A protein (CGA414)
克隆號	LK2H10 + PHE5 + CGA414
亞型	IgG1 + IgG1 + IgG1
基因ID	1113
UniProt ID	P10645
功能	Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
總結(jié)	Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
形式	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF, FC, IP
圖像	Formalin-fixed, paraffin-embedded human small cell lung carcinoma stained with Chromogranin A MAb (LK2H10+PHE5+CGA414)
說明書	Product Datasheet Protocol
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Chromogranin A / CHGA (Neuroendocrine Marker) Antibody - With BSA and Azide