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Monoclonal Antibodies >
Lambda Light Chain (B-Cell Marker) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號(hào) |
AMM00125G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Lambda Light Chain (B-Cell Marker) Antibody - With BSA and Azide.
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分子量 |
~22.5kDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Purified human IgG myeloma proteins coupled to polyaminostyren microbeads
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克隆號(hào) |
HP6054
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亞型 |
IgG2a, kappa
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UniProt ID |
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總結(jié) |
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, FC, IP, E
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圖像 |
Formalin-paraffin human tonsil stained with Lambda Light Chain Ab (HP6054). Note cell membrane & cytoplasmic staining. Western blot analysis of Lambda Light Chain in human intestine using Lambda Light Chain Ab (HP6054). |
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說(shuō)明書(shū) |
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數(shù)量 |
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