品牌 |
Leading Biology |
貨號(hào) |
AMM00121G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Actin, Muscle Specific (Muscle Cell Marker) Antibody - With BSA and Azide.
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分子量 |
Multiple KDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Rat, Rabbit
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靶點(diǎn) |
SDS extract of human myocardium.
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克隆號(hào) |
HHF35
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亞型 |
IgG1, kappa
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通用名 |
ACTSA, ACTVS
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基因ID |
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UniProt ID |
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功能 |
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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總結(jié) |
This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, FC, IP
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圖像 |
Formalin-fixed, paraffin-embedded human leiomyosarcoma (10X) stained with muscle specific actin MAb (HHF35)
Formalin-fixed, paraffin-embedded human leiomyosarcoma (20X) stained with
muscle specific actin MAb (HHF35)
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說(shuō)明書(shū) |
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數(shù)量 |
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