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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > FGF23 (Fibroblast Growth Factor 23) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM00110G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FGF23 (Fibroblast Growth Factor 23) Antibody - With BSA and Azide.
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分子量 |
12-32kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Note=Secretion is dependent on O-glycosylation
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Recombinant human FGF23 protein
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克隆號 |
FGF23/638
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亞型 |
IgG1, kappa
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通用名 |
HYPF
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基因ID |
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UniProt ID |
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功能 |
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
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總結(jié) |
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
E
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說明書 |
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數(shù)量 |
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