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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > MUC2 (Mucin 2) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM00090G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MUC2 (Mucin 2) Antibody - With BSA and Azide.
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分子量 |
520kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Note=In the intestine, secreted into the inner and outer mucus layers.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH.
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克隆號 |
CCP58
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亞型 |
IgG1, kappa
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通用名 |
SMUC
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基因ID |
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UniProt ID |
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功能 |
Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
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總結(jié) |
Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, FC, IP, E
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圖像 |
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說明書 |
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數(shù)量 |
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