品牌 |
Leading Biology |
貨號 |
LM21223 |
產(chǎn)品分類 |
單克隆抗體 |
研究領域 |
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形式 |
Involved in transcriptional regulation. May regulate microRNA (miRNA) expression.
|
濃度 |
This antibody recognizeshuman DUX4. It does notcross-react with DUX4c. |
純度 |
Mouse |
復溶 |
Gabrieels J.,et al.Gene 236:25-32(1999).
Leclercq I.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Oestlund C.,et al.Biochemistry 44:2378-2384(2005).
Mostacciuolo M.L.,et al.Clin. Genet. 75:550-555(2009).
|
儲存條件 |
Human
|
儲存溶液 |
Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}, Double homeobox protein 10 {ECO:0000312|EMBL:AAK91509.1}, DUX4 (HGNC:50800), DUX10
|
應用 |
IHC-P (10 μg/ml), WB (1:1000),
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產(chǎn)品描述 |
Function
Involved in transcriptional regulation. May regulate microRNA (miRNA) expression.
Cellular_Location
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:15709750, ECO:0000269|PubMed:21060811}. Note=Actively transported through the nuclear pore complex (NPC)
Tissue_Location
Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level) (PubMed:21060811). Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells
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數(shù)量 |
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