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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > SPRED1 Antibody

SPRED1 Antibody

LM21203
貨號 貨期 規(guī)格 / 價格 詢價

SPRED1 Antibody

品牌

Leading Biology

貨號

LM21203

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

The protein encoded by this gene is a member of theSprouty family of proteins and is phosphorylated by tyrosine kinasein response to several growth factors. The encoded protein can actas a homodimer or as a heterodimer with SPRED2 to regulateactivation of the MAP kinase cascade. Defects in this gene are acause of neurofibromatosis type 1-like syndrome (NFLS). [providedby RefSeq].

濃度

Purified His-tagged SPRED1 protein(Fragment) was used to produced this monoclonal antibody.

純度

Mouse

試劑準備

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

復溶

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Batz, C., et al. Blood 115(12):2557-2558(2010) Messiaen, L., et al. JAMA 302(19):2111-2118(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Spurlock, G., et al. J. Med. Genet. 46(7):431-437(2009)

儲存條件

Human, Mouse

儲存溶液

Sprouty-related, EVH1 domain-containing protein 1, Spred-1, hSpred1, SPRED1

應(yīng)用

WB~~1:100~250

產(chǎn)品描述

Function Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow (By similarity). Cellular_Location Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein. Nucleus. Note=Localized in cholesterol-rich membrane raft/caveola fractions Tissue_Location Weakly expressed in embryonic cell line HEK293.

數(shù)量

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