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Tyk2 Antibody

LM21163
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

Tyk2 Antibody

品牌

Leading Biology

貨號(hào)

LM21163

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).

濃度

A synthetic peptide corresponding to residues near the C-terminus of human Tyk2 was used as an immunogen.

純度

Rabbit

試劑準(zhǔn)備

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

復(fù)溶

1. Firmback-Kraft I, et al. Oncogene 5(9):1329-36, 1990.<br>2. Velazquez L, et al. Cell 70(2):313-22, 1992.<br>

儲(chǔ)存條件

Human, Mouse, Rat

儲(chǔ)存溶液

Non-receptor tyrosine-protein kinase TYK2, TYK2

應(yīng)用

WB~~1:1000~5000 IHC~~1:100~250

產(chǎn)品描述

Function Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. Tissue_Location Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines

數(shù)量

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