復溶 |
Ligos J.M.,et al.Biochem. Biophys. Res. Commun. 249:380-384(1998).
Berson A.E.,et al.Biochem. Biophys. Res. Commun. 259:533-538(1999).
Ohta S.,et al.Biochem. J. 350:395-404(2000).
Wabakken T.K.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Stairs D.B.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
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儲存溶液 |
Serine/threonine-protein kinase 16, 2.7.11.1, Myristoylated and palmitoylated serine/threonine-protein kinase, MPSK, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, Tyrosine-protein kinase STK16, 2.7.10.2, hPSK, STK16, MPSK1, PKL12, TSF1
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產品描述 |
Function
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Cellular_Location
Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Note=Associates with Golgi and Golgi-derived vesicles.
Tissue_Location
Ubiquitously expressed at very low levels.
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