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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > SLC27A2 Antibody

SLC27A2 Antibody

LM21013
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

SLC27A2 Antibody

品牌

Leading Biology

貨號(hào)

LM21013

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. ; ;

純度

Mouse

復(fù)溶

1. PLoS One. 2011;6(10):e25865. 2. Eur J Cancer. 2011 Feb;47(3):420-7.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Very long-chain acyl-CoA synthetase, VLACS, VLCS, 6.2.1.-, Fatty acid transport protein 2, FATP-2, Fatty-acid-coenzyme A ligase, very long-chain 1, Long-chain-fatty-acid--CoA ligase, 6.2.1.3, Solute carrier family 27 member 2, THCA-CoA ligase, Very long-chain-fatty-acid-CoA ligase, SLC27A2, ACSVL1, FACVL1, FATP2, VLACS

應(yīng)用

E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

產(chǎn)品描述

Function Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity). Cellular_Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. Note=Peripheral membrane associated with the lumenal side of peroxisomes Tissue_Location Expressed in liver, kidney, placenta and pancreas.

數(shù)量

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