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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > OCRL Antibody (clone 4A6)

OCRL Antibody (clone 4A6)

LM20737
貨號 貨期 規(guī)格 / 價格 詢價

OCRL Antibody (clone 4A6)

品牌

Leading Biology

貨號

LM20737

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

形式

Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly.

濃度

Human OCRL

純度

Mouse

復(fù)溶

Attree O.,et al.Nature 358:239-242(1992). Attree O.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. Nussbaum R.L.,et al.Hum. Genet. 99:145-150(1997). Ota T.,et al.Nat. Genet. 36:40-45(2004). Ross M.T.,et al.Nature 434:325-337(2005).

儲存條件

Human

儲存溶液

Inositol polyphosphate 5-phosphatase OCRL-1, 3.1.3.36, Lowe oculocerebrorenal syndrome protein, OCRL, INPP5F, OCRL1

應(yīng)用

IHC-P (5 μg/ml), WB (1:500-1:1000),

產(chǎn)品描述

Function Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly. Cellular_Location Cytoplasmic vesicle, phagosome membrane. Early endosome membrane. Membrane, clathrin-coated pit. Cell projection, cilium, photoreceptor outer segment Cytoplasmic vesicle. Endosome. Golgi apparatus, trans-Golgi network. Note=Also found on macropinosomes Tissue_Location Brain, skeletal muscle, heart, kidney, lung, placenta and fibroblasts. Expressed in the retina and the retinal pigment epithelium.

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