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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > NEU2 Antibody (monoclonal) (M04)

NEU2 Antibody (monoclonal) (M04)

LM20711
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

NEU2 Antibody (monoclonal) (M04)

品牌

Leading Biology

貨號(hào)

LM20711

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments.

濃度

NEU2 (NP_005374, 180 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準(zhǔn)備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復(fù)溶

Defective myogenic differentiation of human rhabdomyosarcoma cells is characterized by sialidase Neu2 loss of expression. Stoppani E, et al. Cell Biol Int, 2009 Sep. PMID 19524683.A nonsynonymous SNP in human cytosolic sialidase in a small Asian population results in reduced enzyme activity: potential link with severe adverse reactions to oseltamivir. Li CY, et al. Cell Res, 2007 Apr. PMID 17426694.Crystal structure of the human cytosolic sialidase Neu2. Evidence for the dynamic nature of substrate recognition. Chavas LM, et al. J Biol Chem, 2005 Jan 7. PMID 15501818.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells. Seyrantepe V, et al. J Biol Chem, 2004 Aug 27. PMID 15213228.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Sialidase-2, Cytosolic sialidase, N-acetyl-alpha-neuraminidase 2, NEU2

應(yīng)用

WB~~1:500~1000

數(shù)量

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