全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
LM20633 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
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濃度 |
Purified His-tagged MAP3K13 protein fragment was used to produced this monoclonal antibody. |
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純度 |
Mouse |
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試劑準(zhǔn)備 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
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復(fù)溶 |
Ikeda A., et al. J. Biochem. 130:773-781(2001).
Masaki M., et al. Eur. J. Biochem. 270:76-83(2003).
Greenman C., et al. Nature 446:153-158(2007).
Sakuma H., et al. J. Biol. Chem. 272:28622-28629(1997).
Ota T., et al. Nat. Genet. 36:40-45(2004).
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儲存條件 |
Human
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儲存溶液 |
Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK, MAP3K13 (HGNC:6852)
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應(yīng)用 |
IF~~1:100
WB~~1:1000
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產(chǎn)品描述 |
Function
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Cellular_Location
Cytoplasm. Membrane; Peripheral membrane protein
Tissue_Location
Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas
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數(shù)量 |
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| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
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| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
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| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購 詢價 |
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