品牌 |
Leading Biology | 貨號(hào) |
LM20632 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
This gene encodes a member of the serine/threonine proteinkinase family. This kinase contains a leucine-zipper domain and ispredominately expressed in neuronal cells. The phosphorylationstate of this kinase in synaptic terminals was shown to beregulated by membrane depolarization via calcineurin. This kinaseforms heterodimers with leucine zipper containing transcriptionfactors, such as cAMP responsive element binding protein (CREB) andMYC, and thus may play a regulatory role in PKA or retinoic acidinduced neuronal differentiation. Alternatively spliced transcriptvariants encoding different proteins have been described.[providedby RefSeq].
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濃度 |
This MAP3K12 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from human MAP3K12. |
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純度 |
Mouse |
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試劑準(zhǔn)備 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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復(fù)溶 |
Clague, J., et al. Mol. Carcinog. 49(2):183-189(2010)
Robitaille, H., et al. J. Invest. Dermatol. 130(1):74-85(2010)
Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) :
Daviau, A., et al. Cell. Signal. 21(4):577-587(2009)
Mukhopadhyay, R., et al. Mol. Cell 32(3):371-382(2008)
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儲(chǔ)存條件 |
Human, Mouse
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儲(chǔ)存溶液 |
Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase, MAP3K12, ZPK
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應(yīng)用 |
WB~~1:800
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產(chǎn)品描述 |
Function
May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
Cellular_Location
Cytoplasm. Membrane; Peripheral membrane protein
Tissue_Location
Highly expressed in brain and kidney.
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數(shù)量 |
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選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價(jià) | |
1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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¥5096.00 | 訂購(gòu) 詢價(jià) | |
2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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¥4950.00 | 訂購(gòu) 詢價(jià) | |
3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
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¥3243.00 | 訂購(gòu) 詢價(jià) | |||
4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
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¥3243.00 | 訂購(gòu) 詢價(jià) | |
5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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¥4015.00 | 訂購(gòu) 詢價(jià) | |
6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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¥5096.00 | 訂購(gòu) 詢價(jià) |
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