品牌 |
Leading Biology |
貨號(hào) |
LM20572 |
產(chǎn)品分類(lèi) |
單克隆抗體 |
研究領(lǐng)域 |
|
形式 |
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
|
濃度 |
Reacts exclusively with cytokeratin 19 which is present in glandular-type epithelia and most carcinomas. Does not react with hepatocytes and hepatocellular carcinoma. |
純度 |
Mouse |
復(fù)溶 |
Stasiak P.C.,et al.Nucleic Acids Res. 15:10058-10058(1987).
Bader B.L.,et al.Eur. J. Cell Biol. 47:300-319(1988).
Eckert R.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1114-1118(1988).
Stasiak P.C.,et al.J. Invest. Dermatol. 92:707-716(1989).
Whittock N.V.,et al.Biochem. Biophys. Res. Commun. 267:462-465(2000).
|
儲(chǔ)存條件 |
Human
|
儲(chǔ)存溶液 |
Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19
|
應(yīng)用 |
Flo (1:100-1:200), IHC-Fr (1:100-1:200), IHC-P (10 μg/ml), WB (1:100-1:1000) ,
|
產(chǎn)品描述 |
Function
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Tissue_Location
Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
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數(shù)量 |
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