品牌 |
Leading Biology |
貨號 |
LM20356 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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純度 |
Mouse |
復(fù)溶 |
1. J Neuroimmune Pharmacol. 2009 Mar;4(1):103-15. 2. Nature. 2006 May 18;441(7091):315-21.
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儲存條件 |
Human, Mouse, Monkey
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儲存溶液 |
Forkhead box protein D3, HNF3/FH transcription factor genesis, FOXD3, HFH2
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應(yīng)用 |
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
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產(chǎn)品描述 |
Function
Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
Cellular_Location
Nucleus.
Tissue_Location
Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined
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數(shù)量 |
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