品牌 |
Leading Biology |
貨號(hào) |
LM20329 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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形式 |
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
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濃度 |
Human Fibrillin 1 |
純度 |
Mouse |
復(fù)溶 |
Pereira L.V.,et al.Hum. Mol. Genet. 2:961-968(1993).
Uyeda T.,et al.J. Hum. Genet. 49:404-407(2004).
Rieder M.J.,et al.Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:671-675(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
|
儲(chǔ)存條件 |
Human
|
儲(chǔ)存溶液 |
Fibrillin-1, FBN1, FBN
|
應(yīng)用 |
IHC-P (5 μg/ml), WB (1:500-1:1000),
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產(chǎn)品描述 |
Function
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
Cellular_Location
Secreted, extracellular space, extracellular matrix
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數(shù)量 |
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