全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
LM20328 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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形式 |
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
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濃度 |
Recognizes human Fibrillin-1. Epitope mapping studies identify the binding site of this antibody to amino-terminal end of the molecule, between amino acid residues 45 and 450. The antibody is reactive with human, chicken, and bovine Fibrillin-1. |
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純度 |
Mouse |
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復(fù)溶 |
Pereira L.V.,et al.Hum. Mol. Genet. 2:961-968(1993).
Uyeda T.,et al.J. Hum. Genet. 49:404-407(2004).
Rieder M.J.,et al.Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:671-675(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
FBN1, ACMICD, Fibrillin 1, Fibrillin-1, FBN, ECTOL1, GPHYSD2, MASS, MFS1, OCTD, SSKS, WMS2, Fibrillin 1 (Marfan syndrome), Fibrillin 15, SGS, WMS
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應(yīng)用 |
IHC-P (10 μg/ml),
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產(chǎn)品描述 |
Function
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
Cellular_Location
Secreted, extracellular space, extracellular matrix
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數(shù)量 |
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