品牌 |
Leading Biology |
貨號 |
LM20327 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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產(chǎn)品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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形式 |
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
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濃度 |
FBLIM1 (NP_060026, 270 a.a. ~ 373 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
純度 |
mouse |
試劑準備 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
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復溶 |
1.Kindlin-1 Is Required for RhoGTPase-Mediated Lamellipodia Formation in Keratinocytes.Has C, Herz C, Zimina E, Qu HY, He Y, Zhang ZG, Wen TT, Gache Y, Aumailley M, Bruckner-Tuderman L.Am J Pathol. 2009 Oct;175(4):1442-52. Epub 2009 Sep 17.
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儲存條件 |
Human
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儲存溶液 |
Filamin-binding LIM protein 1, FBLP-1, Migfilin, Mitogen-inducible 2-interacting protein, MIG2-interacting protein, FBLIM1, FBLP1
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應用 |
WB~~1:500~1000
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數(shù)量 |
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