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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > CORO1A Antibody (monoclonal) (M01)

CORO1A Antibody (monoclonal) (M01)

LM20210
貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)

CORO1A Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號

LM20210

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.

濃度

CORO1A (NP_009005, 360 a.a. ~ 461 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準(zhǔn)備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復(fù)溶

1.Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling.Jayachandran R, Liu X, Bosedasgupta S, Muller P, Zhang CL, Moshous D, Studer V, Schneider J, Genoud C, Fossoud C, Gambino F, Khelfaoui M, Muller C, Bartholdi D, Rossez H, Stiess M, Houbaert X, Jaussi R, Frey D, Kammerer RA, Deupi X, de Villartay JP, Luthi A, Humeau Y, Pieters JPLoS Biol. 2014 Mar 25;12(3):e1001820. doi: 10.1371/journal.pbio.1001820. eCollection 2014 Mar.2.The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients.Federzoni EA, Humbert M, Valk PJ, Behre G, Leibundgut EO, Torbett BE, Fey MF, Tschan MP.Br J Haematol. 2012 Dec 17. doi: 10.1111/bjh.12170.3.Coronin-1 Is Associated with Neutrophil Survival and Is Cleaved during Apoptosis: Potential Implication in Neutrophils from Cystic Fibrosis Patients.Moriceau S, Kantari C, Mocek J, Davezac N, Gabillet J, Guerrera IC, Brouillard F, Tondelier D, Sermet-Gaudelus I, Danel C, Lenoir G, Daniel S, Edelman A, Witko-Sarsat V.J Immunol. 2009 Jun 1;182(11):7254-63.

儲存條件

Human

儲存溶液

Coronin-1A, Coronin-like protein A, Clipin-A, Coronin-like protein p57, Tryptophan aspartate-containing coat protein, TACO, CORO1A, CORO1

應(yīng)用

WB~~1:500~1000

數(shù)量

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