全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
LM20152 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
This gene encodes a membrane glycoprotein of T lymphocytesthat interacts with major histocompatibility complex class IIantigenes and is also a receptor for the human immunodeficiencyvirus. This gene is expressed not only in T lymphocytes, but alsoin B cells, macrophages, and granulocytes. It is also expressed inspecific regions of the brain. The protein functions to initiate oraugment the early phase of T-cell activation, and may function asan important mediator of indirect neuronal damage in infectious andimmune-mediated diseases of the central nervous system. Multiplealternatively spliced transcript variants encoding differentisoforms have been identified in this gene.
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濃度 |
This CD4 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human CD4. |
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純度 |
Mouse |
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試劑準(zhǔn)備 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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復(fù)溶 |
Pourgheysari, B., et al. Blood 116(16):2968-2974(2010)
Rudd, C.E., et al. J. Immunol. 185(5):2645-2649(2010)
Ammirati, E., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1832-1841(2010)
Schenkel, J.M., et al. J. Immunol. 185(4):2013-2019(2010)
Lee, K.M., et al. Am. J. Hematol. 85(8):560-563(2010)
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儲存條件 |
Human
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儲存溶液 |
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4, CD4
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應(yīng)用 |
WB~~1:100~800
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產(chǎn)品描述 |
Function
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Cellular_Location
Cell membrane; Single-pass type I membrane protein Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum
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數(shù)量 |
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| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購 詢價 | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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￥4950.00 | 訂購 詢價 | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
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￥3243.00 | 訂購 詢價 | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
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￥3243.00 | 訂購 詢價 | |
| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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￥4015.00 | 訂購 詢價 | |
| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購 詢價 |
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