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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > CD4 Antibody

CD4 Antibody

LM20151
貨號 貨期 規(guī)格 / 價格 詢價

CD4 Antibody

品牌

Leading Biology

貨號

LM20151

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

純度

Mouse

復(fù)溶

1. M Benkirane J Virol. 1995 November; 69(11): 6898–6903.

儲存條件

Human

儲存溶液

T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4, CD4

應(yīng)用

FC~~1/200 - 1/400

產(chǎn)品描述

Function Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. Cellular_Location Cell membrane; Single-pass type I membrane protein Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum

數(shù)量

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