全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
LM20119 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
CCR7, or C-C chemokine receptor type 7, is a G protein-coupled, seven-transmembrane domain receptor protein. Originally identified as the EBV-induced gene-1 (1), CCR7 was later found to be the receptor for the chemokines CCL21 (SLC, 6Ckine, Exodus-2) (3) and CCL19 (MIP-3, Exodus-3, ELC) (4). CCR7 is expressed in lymphoid tissues and activated B and T lymphocytes (2). It is up-regulated in B cells infected with Epstein-Barr virus and T cells infected with herpesvirus 6 or 7 (4).
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濃度 |
A synthetic peptide corresponding to residues in loop-3 extracellular domain of human C-C chemokine receptor type 7 was used as immunogen. The antibody does not cross-react with other CKR family members. Predicted to cross-react with pig and bovine based on sequence homology. |
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純度 |
Rabbit |
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試劑準(zhǔn)備 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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復(fù)溶 |
1. Schweickart, V. L., et al. Cloning of human and mouse EBI1, a lymphoid-specific G-protein-coupled receptor encoded on human chromosome 17q12-q21.2. Genomics. 23: 643<br>2. Birkenbach, M., et al. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. J. Virol. 67: 2209<br>3. Yoshida, R., et al. Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. J. Biol. Chem. 273: 7118<br>4. Yoshida, R., et al. Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7. J. Biol. Chem. 272: 13803<br>
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儲(chǔ)存條件 |
Human, Mouse
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儲(chǔ)存溶液 |
C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD197, CCR7, CMKBR7, EBI1, EVI1
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應(yīng)用 |
WB~~1:500
FC~~1:20
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產(chǎn)品描述 |
Function
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Cellular_Location
Cell membrane; Multi-pass membrane protein.
Tissue_Location
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7
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數(shù)量 |
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| 選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價(jià) | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購 詢價(jià) | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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￥4950.00 | 訂購 詢價(jià) | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
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￥3243.00 | 訂購 詢價(jià) | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
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￥3243.00 | 訂購 詢價(jià) | |
| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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￥4015.00 | 訂購 詢價(jià) | |
| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購 詢價(jià) |
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