品牌 |
Leading Biology |
貨號 |
LM20118 |
產(chǎn)品分類 |
單克隆抗體 |
研究領域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
The protein encoded by this gene is a member of the Gprotein-coupled receptor family. This receptor was identified as agene induced by the Epstein-Barr virus (EBV), and is thought to bea mediator of EBV effects on B lymphocytes. This receptor isexpressed in various lymphoid tissues and activates B and Tlymphocytes. It has been shown to control the migration of memory Tcells to inflamed tissues, as well as stimulate dendritic cellmaturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) hasbeen reported to be a specific ligand of this receptor. [providedby RefSeq].
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濃度 |
This CCR7 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 11-37 amino acids from the N-terminal region of human CCR7. |
純度 |
Mouse |
試劑準備 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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復溶 |
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Deguchi, K., et al. Anticancer Res. 30(6):2361-2366(2010)
Raynaud, C.M., et al. Clin Lung Cancer 11(3):187-191(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
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儲存條件 |
Human
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儲存溶液 |
C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD197, CCR7, CMKBR7, EBI1, EVI1
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應用 |
WB~~1:200~3200
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產(chǎn)品描述 |
Function
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Cellular_Location
Cell membrane; Multi-pass membrane protein.
Tissue_Location
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7
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數(shù)量 |
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