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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > VRK2 Antibody (monoclonal) (M01)

VRK2 Antibody (monoclonal) (M01)

LM21183
貨號 貨期 規(guī)格 / 價格 詢價

VRK2 Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號

LM21183

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to phosphorylate casein and undergo autophosphorylation. Multiple alternatively spliced transcript variants have been found for this gene.

濃度

VRK2 (AAH27854, 260 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準(zhǔn)備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復(fù)溶

Common variants conferring risk of schizophrenia. Stefansson H, et al. Nature, 2009 Aug 6. PMID 19571808.Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities. Sanz-Garc?a M, et al. Mol Cell Proteomics, 2008 Nov. PMID 18617507.The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53. Valbuena A, et al. PLoS One, 2008 Jul 9. PMID 18612383.Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein. Blanco S, et al. PLoS One, 2008 Feb 20. PMID 18286207.Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1. Blanco S, et al. Mol Cell Biol, 2007 Oct. PMID 17709393.

儲存條件

Human

儲存溶液

Serine/threonine-protein kinase VRK2, Vaccinia-related kinase 2, VRK2

應(yīng)用

WB~~1:500~1000

數(shù)量

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