Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

TMEPAI (AAH15918, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

mouse

Clear, colorless solution in phosphate buffered saline, pH 7.2.

1.Mutation or Loss of p53 Differentially Modifies TGFβ Action in Ovarian CancerO Hainmhire E, Quartuccio SM, Cheng W, Ahmed RA, King SM, Burdette JEPLoS One. 2014 Feb 20;9(2):e89553. doi: 10.1371/journal.pone.0089553. eCollection 2014.2.TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways.Hu Y, He K, Wang D, Yuan X, Liu Y, Ji H, Song JCarcinogenesis. 2013 Apr 24.3.Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma.Costea DE, Hills A, Osman AH, Thurlow J, Kalna G, Huang X, Pena Murillo C, Parajuli H, Suliman S, Keerthi KK, Johannessen AC, Partridge MCancer Res. 2013 Apr 18.4.Transforming Growth Factor-{beta} (TGF-{beta})-Inducible Gene TMEPAI Converts TGF-{beta} from a Tumor Suppressor to a Tumor Promoter in Breast Cancer.Singha PK, Yeh IT, Venkatachalam MA, Saikumar P.Cancer Res. 2010 Jul 7. [Epub ahead of print]5.TMEPAI, a Transmembrane TGF-beta-Inducible Protein, Sequesters Smad Proteins from Active Participation in TGF-beta Signaling.Watanabe Y, Itoh S, Goto T, Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L, Tanaka A, Nakano N, Mommaas AM, Shibuya H, Ten Dijke P, Kato M.Mol Cell. 2010 Jan 15;37(1):123-34.6.A feedback loop between the androgen receptor and a NEDD4 binding protein, PMEPA1 in prostate cancer cells.Li H, Xu LL, Masuda K, Raymundo E, McLeod DG, Dobi A, Srivastava S.J Biol Chem. 2008 Oct 24;283(43):28988-95. Epub 2008 Aug 14.7.High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone.Hirokawa YS, Takagi A, Uchida K, Kozuka Y, Yoneda M, Watanabe M, Shiraishi T.Cell Mol Biol Lett. 2007 Feb 17; [Epub ahead of print]

Human

Protein TMEPAI, Prostate transmembrane protein androgen induced 1, Solid tumor-associated 1 protein, Transmembrane prostate androgen-induced protein, PMEPA1, STAG1, TMEPAI

WB~~1:500~1000