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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > TLE4 Antibody (Center)(Ascites)

TLE4 Antibody (Center)(Ascites)

LM21113
貨號 貨期 規(guī)格 / 價格 詢價

TLE4 Antibody (Center)(Ascites)

品牌

Leading Biology

貨號

LM21113

產(chǎn)品分類

單克隆抗體

研究領域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

濃度

This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.

純度

Mouse

試劑準備

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

復溶

Liu, Y., et al. PLoS Genet. 5 (11), E1000707 (2009) : Hancock, D.B., et al. PLoS Genet. 5 (8), E1000623 (2009) : Stolk, L., et al. Nat. Genet. (2009) In press : Dayyani, F., et al. Blood 111(8):4338-4347(2008) Heimbucher, T., et al. Mol. Cell. Biol. 27(1):340-351(2007)

儲存條件

Human

儲存溶液

Transducin-like enhancer protein 4, Grg-4, Groucho-related protein 4, TLE4, GRG4, KIAA1261

應用

WB~~1:100~3200

產(chǎn)品描述

Function Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity). Cellular_Location Nucleus. Tissue_Location In all tissues examined, mostly in brain, and muscle

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