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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > TCOF1 Antibody (monoclonal) (M02)

TCOF1 Antibody (monoclonal) (M02)

LM21089
貨號 貨期 規(guī)格 / 價格 詢價

TCOF1 Antibody (monoclonal) (M02)

品牌

Leading Biology

貨號

LM21089

產(chǎn)品分類

單克隆抗體

研究領域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.

濃度

TCOF1 (NP_001008657, 2 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復溶

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Reduced transcription of TCOF1 in adult cells of Treacher Collins syndrome patients. Masotti C, et al. BMC Med Genet, 2009 Dec 14. PMID 20003452.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Treacle recruits RNA polymerase I complex to the nucleolus that is independent of UBF. Lin CI, et al. Biochem Biophys Res Commun, 2009 Aug 21. PMID 19527688.

儲存條件

Human

儲存溶液

Treacle protein, Treacher Collins syndrome protein, TCOF1

應用

WB~~1:500~1000

數(shù)量

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