品牌 |
Leading Biology |
貨號(hào) |
LM21074 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
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純度 |
Mouse |
復(fù)溶 |
1. Hum Pathol. 2013 Apr;44(4):472-9. 2. Cytogenet Genome Res. 2010;128(1-3):162-8.
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
Synaptonemal complex protein 3, SCP-3, SYCP3, SCP3
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應(yīng)用 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
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產(chǎn)品描述 |
Function
Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).
Cellular_Location
Nucleus. Chromosome. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.
Tissue_Location
Testis-specific.
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數(shù)量 |
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