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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > STC2 Antibody

STC2 Antibody

LM21053
貨號 貨期 規(guī)格 / 價格 詢價

STC2 Antibody

品牌

Leading Biology

貨號

LM21053

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

This gene encodes a secreted, homodimeric glycoproteinthat is expressed in a wide variety of tissues and may haveautocrine or paracrine functions. The encoded protein has 10 of its15 cysteine residues conserved among stanniocalcin family membersand is phosphorylated by casein kinase 2 exclusively on its serineresidues. Its C-terminus contains a cluster of histidine residueswhich may interact with metal ions. The protein may play a role inthe regulation of renal and intestinal calcium and phosphatetransport, cell metabolism, or cellular calcium/phosphatehomeostasis. Constitutive overexpression of human stanniocalcin 2in mice resulted in pre- and postnatal growth restriction, reducedbone and skeletal muscle growth, and organomegaly. Expression ofthis gene is induced by estrogen and altered in some breastcancers.

濃度

This STC2 monoclonal antibody is generated from mouse immunized with STC2 recombinant protein.

純度

Mouse

試劑準備

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

復溶

Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) : Law, A.Y., et al. Exp. Cell Res. 316(3):466-476(2010) Volland, S., et al. Int. J. Cancer 125(9):2049-2057(2009) Ieta, K., et al. Int. J. Cancer 125(4):926-931(2009) Tamura, K., et al. Cancer Sci. 100(5):914-919(2009)

儲存條件

Human

儲存溶液

Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2

應用

WB~~1:100~250

產(chǎn)品描述

Function Has an anti-hypocalcemic action on calcium and phosphate homeostasis. Cellular_Location Secreted. Tissue_Location Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes

數(shù)量

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