全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
LM21051 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
|
形式 |
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
|
||
濃度 |
This Protein-A purified antibody is directed against human STAT2 protein. A BLAST analysis was used to suggest cross-reactivity with STAT2 protein from human, rat (73%) and mouse (76%), sources based on homology with the immunizing sequence. Reactivi ... |
||
純度 |
Mouse |
||
復(fù)溶 |
Fu X.-Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:7840-7843(1992).
Yan R.,et al.Nucleic Acids Res. 23:459-463(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Fu X.Y.,et al.Cell 70:323-335(1992).
|
||
儲存條件 |
Human, Mouse
|
||
儲存溶液 |
Signal transducer and activator of transcription 2, p113, STAT2
|
||
應(yīng)用 |
ELISA (1:5000-1:10000), IHC-P (10 μg/ml), WB (1:1000)
|
||
產(chǎn)品描述 |
Function
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Cellular_Location
Cytoplasm. Nucleus. Note=Translocated into the nucleus upon activation by IFN-alpha/beta
|
||
數(shù)量 |
|
||
| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價(jià) | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
￥5096.00 | 訂購 詢價(jià) | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
|
￥4950.00 | 訂購 詢價(jià) | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
|
￥3243.00 | 訂購 詢價(jià) | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
|
￥3243.00 | 訂購 詢價(jià) | |
| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
|
￥4015.00 | 訂購 詢價(jià) | |
| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
￥5096.00 | 訂購 詢價(jià) |
微信掃描二維碼，隨時(shí)隨地與小諾親密接觸，精彩活動，勁爆優(yōu)惠，觸手可得！
銷售-華東區(qū)