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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > SRA Antibody

SRA Antibody

LM21041
貨號 貨期 規(guī)格 / 價格 詢價

SRA Antibody

品牌

Leading Biology

貨號

LM21041

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

純度

Mouse

復(fù)溶

1. Rainer B. Lanz, Steven S. Chua, Niall Barron. Mol. Cell. Biol, Oct 2003; 23: 7163 - 7176. 2. Shilpa Chooniedass-Kothari, Mohammad Kariminia Hamedani, Sandy Troup. Int J Cancer. 2006 Feb 15;118(4):1054-9 3. S. Chooniedass-Kothari, E. Emberley, M. K. Hamedani. FEBS Lett. 2004 May 21;566(1-3):43-7.

儲存條件

Human

儲存溶液

Steroid receptor RNA activator 1, Steroid receptor RNA activator protein, SRAP, SRA1 (HGNC:11281)

應(yīng)用

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

產(chǎn)品描述

Function Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. Cellular_Location Nucleus. Cytoplasm Tissue_Location Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up- regulated in human tumors of the breast, ovary, and uterus

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