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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > SMAD7 Antibody (monoclonal) (M09)

SMAD7 Antibody (monoclonal) (M09)

LM21023
貨號 貨期 規(guī)格 / 價格 詢價

SMAD7 Antibody (monoclonal) (M09)

品牌

Leading Biology

貨號

LM21023

產(chǎn)品分類

單克隆抗體

研究領域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

濃度

SMAD7 (NP_005895, 160 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

Mouse

試劑準備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復溶

1.Aberrant expression in multiple components of the transforming growth factor-?]1-induced Smad signaling pathway during 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell carcinogenesis.Chen YK, Yang SH, Huang AH, Hsue SS, Lin LM.Oral Oncol. 2011 Feb 26. [Epub ahead of print]

儲存條件

Human

儲存溶液

Mothers against decapentaplegic homolog 7, MAD homolog 7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 8, MAD homolog 8, Mothers against DPP homolog 8, SMAD family member 7, SMAD 7, Smad7, hSMAD7, SMAD7, MADH7, MADH8

應用

WB~~1:500~1000

數(shù)量

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