儲存溶液 |
Protein phosphatase Slingshot homolog 1, 3.1.3.16, 3.1.3.48, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L
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產(chǎn)品描述 |
Function
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Cellular_Location
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion Also localized to the cleavage furrow and the midbody during cytokinesis
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