全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
LM20989 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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形式 |
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
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濃度 |
SGCA (NP_000014.1, 26 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
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純度 |
mouse |
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試劑準(zhǔn)備 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
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復(fù)溶 |
Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts. Fernandez K, et al. Am J Pathol, 2010 Jan. PMID 20019182.Sarcoglycanopathies: can muscle immunoanalysis predict the genotype? Klinge L, et al. Neuromuscul Disord, 2008 Dec. PMID 18996010.Identification of two E-boxes that negatively modulate the activity of MyoD on the alpha-sarcoglycan core promoter. Delgado-Olgu?n P, et al. Biochim Biophys Acta, 2008 Jan. PMID 18078839.Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development. Rafii MS, et al. J Cell Physiol, 2006 Nov. PMID 16883602.Sarcoglycanopathies and the risk of undetected deletion alleles in diagnosis. White SJ, et al. Hum Mutat, 2005 Jul. PMID 15954112.
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儲存條件 |
Human
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儲存溶液 |
Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin, Dystroglycan-2, SGCA, ADL, DAG2
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應(yīng)用 |
WB~~1:500~1000
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數(shù)量 |
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| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購 詢價 | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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￥4950.00 | 訂購 詢價 | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
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￥3243.00 | 訂購 詢價 | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
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￥3243.00 | 訂購 詢價 | |
| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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￥4015.00 | 訂購 詢價 | |
| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
￥5096.00 | 訂購 詢價 |
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