全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
LM20969 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
|
產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
||
形式 |
The protein encoded by this gene is an atypical member ofthe family of growth factor receptor protein tyrosine kinases,differing from other members at a number of conserved residues inthe activation and nucleotide binding domains. This gene productbelongs to a subfamily whose members do not appear to be regulatedby phosphorylation in the activation segment. It has been suggestedthat mediation of biological activity by recruitment of asignaling-competent auxiliary protein may occur through an as yetuncharacterized mechanism. Two alternative splice variants havebeen identified, encoding distinct isoforms.
|
||
濃度 |
This RYK monoclonal antibody is generated from mouse immunized with RYK recombinant protein. |
||
純度 |
Mouse |
||
試劑準備 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
|
||
復溶 |
Carter, T.C., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(2):84-93(2010)
Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):251-257(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Szafranski, K., et al. Genome Biol. 8 (8), R154 (2007) :
Watanabe, A., et al. Cleft Palate Craniofac. J. 43(3):310-316(2006)
|
||
儲存條件 |
Human
|
||
儲存溶液 |
Tyrosine-protein kinase RYK, RYK, JTK5A
|
||
應用 |
WB~~1:100~500
|
||
產(chǎn)品描述 |
Function
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Cellular_Location
Membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus.
Tissue_Location
Observed in all the tissues examined.
|
||
數(shù)量 |
|
||
| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
￥5096.00 | 訂購 詢價 | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
|
￥4950.00 | 訂購 詢價 | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
|
￥3243.00 | 訂購 詢價 | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
|
￥3243.00 | 訂購 詢價 | |
| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
|
￥4015.00 | 訂購 詢價 | |
| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
￥5096.00 | 訂購 詢價 |
微信掃描二維碼，隨時隨地與小諾親密接觸，精彩活動，勁爆優(yōu)惠，觸手可得！
銷售-華東區(qū)