全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
LM20944 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a tyrosine protein kinase receptor which is required for cartilage and growth plate development. As a member of the receptor protein kinases (RTKs) family, ROR2 is commonly found in embryonic kidney, but its function has not been fully understood. ROR2 has been linked to embryonic development due its involvement in WNT signaling pathway. Additionally, ROR2 has been shown to be critical for the formation of skeleton, heart, and genitals. Specifically, ROR2 phosphorylates 14-3-3 protein beta/alpha which leads to induction of osterogenesis and bone formation (2). A mutation in ROR2 is commonly seen in Robinow syndrome and autosomal dominant brachydactyly B disorders (3).
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濃度 |
A synthetic peptide corresponding to residues of human ROR2 was used as an immunogen. |
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純度 |
Rabbit |
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試劑準(zhǔn)備 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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復(fù)溶 |
1. Smithgall TE et al., Crit. Rev. Oncog. 9:43-62, 1998. 2. Liu Y et al., Molecular Endocrinology 21(12):3050-3061, 2007. 3. Oldridge M. et al. Nature Genetics 24:275 - 278, 2000.
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
Tyrosine-protein kinase transmembrane receptor ROR2, Neurotrophic tyrosine kinase, receptor-related 2, ROR2, NTRKR2
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應(yīng)用 |
WB~~1:500
FC~~1:10~100
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產(chǎn)品描述 |
Function
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.
Cellular_Location
Cell membrane; Single-pass type I membrane protein
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數(shù)量 |
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| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價(jià) | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
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| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購 詢價(jià) |
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