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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > RIN2 Antibody (monoclonal) (M01)

RIN2 Antibody (monoclonal) (M01)

LM20940
貨號 貨期 規(guī)格 / 價格 詢價

RIN2 Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號

LM20940

產品分類

單克隆抗體

研究領域

產品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family.

濃度

RIN2 (NP_061866, 786 a.a. ~ 894 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復溶

The RIN2 syndrome: a new autosomal recessive connective tissue disorder caused by deficiency of Ras and Rab interactor 2 (RIN2). Syx D, et al. Hum Genet, 2010 Jul. PMID 20424861.RIN2 deficiency results in macrocephaly, alopecia, cutis laxa, and scoliosis: MACS syndrome. Basel-Vanagaite L, et al. Am J Hum Genet, 2009 Aug. PMID 19631308.Involvement of the Ras-Ras-activated Rab5 guanine nucleotide exchange factor RIN2-Rab5 pathway in the hepatocyte growth factor-induced endocytosis of E-cadherin. Kimura T, et al. J Biol Chem, 2006 Apr 14. PMID 16423831.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway. Kajiho H, et al. J Cell Sci, 2003 Oct 15. PMID 12972505.

儲存條件

Human

儲存溶液

Ras and Rab interactor 2, Ras association domain family 4, Ras inhibitor JC265, Ras interaction/interference protein 2, RIN2, RASSF4

應用

WB~~1:500~1000

數量

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