品牌 |
Leading Biology |
貨號 |
LM20915 |
產(chǎn)品分類 |
單克隆抗體 |
研究領域 |
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形式 |
Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.
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濃度 |
Human RAPGEF6 |
純度 |
Mouse |
復溶 |
Kuiperij H.B.,et al.Biochim. Biophys. Acta 1593:141-149(2003).
Banville D.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Gao X.,et al.J. Biol. Chem. 276:42219-42225(2001).
Schmutz J.,et al.Nature 431:268-274(2004).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
|
儲存條件 |
Human
|
儲存溶液 |
Rap guanine nucleotide exchange factor 6, PDZ domain-containing guanine nucleotide exchange factor 2, PDZ-GEF2, RA-GEF-2, RAPGEF6, PDZGEF2
|
應用 |
IF (40 μg/ml), IHC-P (5 μg/ml), WB (1:500-1:1000)
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產(chǎn)品描述 |
Function
Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.
Cellular_Location
Cytoplasm. Cell membrane. Note=Upon binding to M-Ras, it translocates to the plasma membrane
Tissue_Location
Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas
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數(shù)量 |
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