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RAB14 Antibody

LM20872
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

RAB14 Antibody

品牌

Leading Biology

貨號(hào)

LM20872

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion.

濃度

This RAB14 antibody is generated from a mouse immunized with a recombinant protein of human RAB14.

純度

Mouse

試劑準(zhǔn)備

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

復(fù)溶

Proikas-Cezanne T.,et al.Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases. Ren Y.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases. Huang Y.-P.,et al.Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000). Bechtel S.,et al.BMC Genomics 8:399-399(2007).

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Ras-related protein Rab-14, RAB14

應(yīng)用

WB~~1:2000

產(chǎn)品描述

Function Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion. Cellular_Location Recycling endosome. Early endosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome Cytoplasmic vesicle, phagosome membrane; Lipid- anchor; Cytoplasmic side Note=Recruited to recycling endosomes by DENND6A. Recruited to phagosomes containing S.aureus or M.tuberculosis

數(shù)量

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