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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > PGEA1 Antibody (monoclonal) (M06)

PGEA1 Antibody (monoclonal) (M06)

LM20788
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

PGEA1 Antibody (monoclonal) (M06)

品牌

Leading Biology

貨號(hào)

LM20788

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

濃度

CBY1 (NP_056188, 18 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準(zhǔn)備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復(fù)溶

Chibby interacts with NBPF1 and clusterin, two candidate tumor suppressors linked to neuroblastoma. Vandepoele K, et al. Exp Cell Res, 2010 Apr 15. PMID 20096688.Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling. Li FQ, et al. Mol Biol Cell, 2010 Jan 15. PMID 19940019.Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. Menon R, et al. Reprod Biol Endocrinol, 2009 Jun 15. PMID 19527514.Chibby forms a homodimer through a heptad repeat of leucine residues in its C-terminal coiled-coil motif. Mofunanya A, et al. BMC Mol Biol, 2009 May 12. PMID 19435523.Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. Velez DR, et al. Am J Obstet Gynecol, 2009 Feb. PMID 19019335.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Protein chibby homolog 1, ARPP-binding protein, Cytosolic leucine-rich protein, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, CBY1, ARB1, C22orf2, CBY, PGEA1

應(yīng)用

WB~~1:500~1000

數(shù)量

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