復(fù)溶 |
Fisher D.A.,et al.J. Biol. Chem. 273:15559-15564(1998).
Guipponi M.,et al.Hum. Genet. 103:386-392(1998).
Rentero C.,et al.Biochem. Biophys. Res. Commun. 301:686-692(2003).
Wang P.,et al.Gene 314:15-27(2003).
Rentero C.,et al.BMC Mol. Biol. 7:39-39(2006).
|
產(chǎn)品描述 |
Function
Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.
Cellular_Location
Isoform PDE9A1: Cell projection, ruffle membrane. Cytoplasm, perinuclear region. Golgi apparatus Endoplasmic reticulum Isoform PDE9A3: Cytoplasm. Endoplasmic reticulum
Tissue_Location
Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate
|