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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > PACSIN2 Antibody

PACSIN2 Antibody

LM20763
貨號 貨期 規(guī)格 / 價格 詢價

PACSIN2 Antibody

品牌

Leading Biology

貨號

LM20763

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

濃度

This PACSIN2 antibody is generated from a mouse immunized with a recombinant protein between 250-486 amino acids from human PACSIN2.

純度

Mouse

試劑準(zhǔn)備

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

復(fù)溶

Ritter B.,et al.FEBS Lett. 454:356-362(1999). Wiemann S.,et al.Genome Res. 11:422-435(2001). Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004). Dunham I.,et al.Nature 402:489-495(1999). Modregger J.,et al.J. Cell Sci. 113:4511-4521(2000).

儲存條件

Human, Mouse

儲存溶液

Protein kinase C and casein kinase substrate in neurons protein 2, Syndapin-2, Syndapin-II, PACSIN2

應(yīng)用

WB~~1:2000

產(chǎn)品描述

Function Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis. Cellular_Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome Recycling endosome membrane. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Membrane, caveola. Note=Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1 Tissue_Location Widely expressed.

數(shù)量

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