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全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
LM20751 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
p115 / TAP (Vesicle docking protein p115, Transcytosis-associated protein) is a general vesicular transport factor located in the Golgi complex. p115 is part of the Golgin protein family, defined by their location in the Golgi matrix and their long coiled-coil domain. p115 is thought to be essential for ER to Golgi traffic (1). Specifically, p115 is required for intercisternal transportation within the Golgi stack and required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane (2). Also, p115 has been suggested to be act as a vesicular anchor to the target membrane.
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濃度 |
A synthetic peptide corresponding to residues near the N-terminus of human p115 was used as an immunogen. |
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純度 |
Rabbit |
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試劑準(zhǔn)備 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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復(fù)溶 |
1. Alvarez C et al., JBC 276(4):2693-2700, 2001.<br>2. Shorter J, Warren G et al., JBC 146(1):57-70, 1999.<br>
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儲(chǔ)存條件 |
Human, Mouse, Rat
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儲(chǔ)存溶液 |
General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein, USO1, VDP
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應(yīng)用 |
WB~~1:500
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產(chǎn)品描述 |
Function
General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
Cellular_Location
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Note=Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes
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數(shù)量 |
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