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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > NCOA4 Antibody

NCOA4 Antibody

LM20705
貨號 貨期 規(guī)格 / 價格 詢價

NCOA4 Antibody

品牌

Leading Biology

貨號

LM20705

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

This gene encodes an androgen receptor coactivator. Theencoded protein interacts with the androgen receptor in aligand-dependent manner to enhance its transcriptional activity.Chromosomal translocations between this gene and the ret tyrosinekinase gene, also located on chromosome 10, have been associatedwith papillary thyroid carcinoma. Alternatively spliced transcriptvariants have been described. Pseudogenes are present onchromosomes 4, 5, 10, and 14.

濃度

Purified His-tagged NCOA4 protein(Fragment) was used to produced this monoclonal antibody.

純度

Mouse

試劑準(zhǔn)備

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

復(fù)溶

Sadow, P.M., et al. Endocr. Pathol. 21(2):73-79(2010) Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) : Richardson, D.S., et al. Cancer Res. 69(11):4861-4869(2009) Peng, Y., et al. Am. J. Pathol. 172(1):225-235(2008) Bongarzone, I., et al. Genomics 42(2):252-259(1997)

儲存條件

Human

儲存溶液

Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1, NCOA4, ARA70, ELE1, RFG

應(yīng)用

WB~~1:100~250

產(chǎn)品描述

Function Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. Tissue_Location Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis

數(shù)量

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