全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
LM20688 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
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濃度 |
This MYO18B antibody is generated from a mouse immunized with recombinant protein from human MYO18B. |
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純度 |
Mouse |
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試劑準(zhǔn)備 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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復(fù)溶 |
Nishioka M.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:12269-12274(2002).
Salamon M.,et al.J. Mol. Biol. 326:137-149(2003).
Gu Y.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Dunham I.,et al.Nature 402:489-495(1999).
Stanchi F.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
Unconventional myosin-XVIIIb, MYO18B
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應(yīng)用 |
IHC-P~~1:25
FC~~1:25
WB~~1:16000
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產(chǎn)品描述 |
Function
May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
Cellular_Location
Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiated myoblasts Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes
Tissue_Location
Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus
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數(shù)量 |
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