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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > Moesin Antibody [Clone MSN491]

Moesin Antibody [Clone MSN491]

LM20677
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

Moesin Antibody [Clone MSN491]

品牌

Leading Biology

貨號(hào)

LM20677

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at 2 to 8°C.Antibody is stable for 24 months.

形式

Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

濃度

Recombinant human Moesin protein

純度

Mouse

試劑準(zhǔn)備

0.5 ml at 200ug/ml with BSA and azide

復(fù)溶

1. Lankes W et. al., Biochem Journal, 1988; 251:831-842. 2. Schwartz-Albiez R et. al., European Journal Cell Biology, 1995; 67:189-198.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Moesin, Membrane-organizing extension spike protein, MSN

產(chǎn)品描述

Function Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. Cellular_Location Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. {ECO:0000250, ECO:0000269|PubMed:18586956} Tissue_Location In all tissues and cultured cells studied.

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