品牌 |
Leading Biology | 貨號 |
LM20675 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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形式 |
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
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濃度 |
Human MLKL |
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純度 |
Mouse |
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復(fù)溶 |
Manning G.,et al.Science 298:1912-1934(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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儲存條件 |
Human
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儲存溶液 |
Mixed lineage kinase domain-like protein, hMLKL, MLKL {ECO:0000312|EMBL:AAH28141.1}
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應(yīng)用 |
IHC-P (10 μg/ml)
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產(chǎn)品描述 |
Function
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Cellular_Location
Cytoplasm. Cell membrane. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction
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數(shù)量 |
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選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
¥5096.00 | 訂購 詢價 | |
2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
|
¥4950.00 | 訂購 詢價 | |
3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
|
¥3243.00 | 訂購 詢價 | |||
4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
|
¥3243.00 | 訂購 詢價 | |
5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
|
¥4015.00 | 訂購 詢價 | |
6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
¥5096.00 | 訂購 詢價 |
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